TABLE 1.
Diagnostic performance of AMPLICOR PCR in detection of urogenital N. gonorrhoeae infection among 342 FSWs from Cotonou, Benina
| Specimen | % of women with positive test (n = 342) | Sensitivityb | Specificityb | Positive predictive value | Negative predictive value |
|---|---|---|---|---|---|
| Urine | 13.5 | 43/80 (53.8) | 259/262 (98.9) | 43/46 (93.5) | 259/296 (87.5) |
| 2-SP swab | 21.9 | 75/82 (91.5) | 260/260 (100) | 75/75 (100) | 260/267 (97.4) |
| Dry swab | 25.4 | 77/80 (96.3) | 252/262 (96.2) | 77/87 (88.5) | 252/255 (98.8) |
a
The validity parameters for each type of specimen were calculated using a rotating independent standard that included all the other tests but not the test being evaluated. Data for sensitivity, specificity, and positive and negative predictive value are numbers of correctly identified specimens/total number tested, with percentages in parentheses.
b
Using the latent-class model, the sensitivity and specificity of the Amplicor PCR with urine were 56.0 and 99.0%. Corresponding figures for the wet swab were 98.0 and 100%, respectively, and for the dry swab were 100 and 96.0%, respectively.