Table 1:
Baseline Characteristics of Patients by Treatment Group*
| Characteristic | Hydromorphone (N=66†) |
Morphine (N=68†) |
P value |
|---|---|---|---|
| Age (years) | 31.4±4.3 | 31.9±4.3 | 0.411 |
| Height (cm) | 164.6±7.2 | 165.4±6.7 | 0.407 |
| Weight (kg) | 77.8±19.2 | 78.3±18.2 | 0.735 |
| Body Mass Index (kg/m2) | 28.6±6.4 | 28.5±6.2 | 0.942 |
| Gravidity | 0.216 | ||
| 1 | 9 (14) | 10 (15) | |
| 2 | 25 (38) | 34 (50) | |
| 3 | 21 (32) | 16 (24) | |
| ≥4 | 11 (16) | 8 (12) | |
| Parity | 0.534 | ||
| 0 | 11 (17) | 13 (19) | |
| 1 | 33 (50) | 35 (51) | |
| 2 | 18 (27) | 18 (26) | |
| ≥3 | 4 (6) | 2 (3) | |
| Previous cesareans | 0.850 | ||
| 0 | 18 (27) | 19 (28) | |
| 1 | 35 (53) | 37 (54) | |
| ≥2 | 13 (20) | 12 (18) | |
| Tubal Ligation | 0.313 | ||
| No | 53 (80) | 59 (87) | |
| Yes | 13 (20) | 9 (13) | |
| Time of spinal placement | 0.290 | ||
| 06:00 – 09:59 | 49 (74) | 41 (60) | |
| 10:00 – 13:59 | 15 (23) | 24 (35) | |
| 14:00 – 17:59 | 1 (2) | 3 (4) | |
| 18:00 – 21:59 | 1 (2) | 0 (0) | |
| Duration of Surgery (minutes) | 0.369 | ||
| median (25th, 75th) | 59 (51, 69) | 62 (50, 78) | |
| min, max | 35 to 111 | 30 to 204 | |
| Gestational age (weeks) | 0.173 | ||
| median (25th, 75th) | 39.0 (39.0, 39.2) | 39.1 (39.0, 39.2) | |
| Range | 37.0 to 40.4 | 37.0 to 40.3 | |
| Fetal weight* (g) | 0.393 | ||
| median (25th, 75th) | 3410 (3070, 3685) | 3460 (3250, 3730) | |
| Range | 2090 to 4440 | 2590 to 4370 | |
| Apgar at 1 minute* | 0.496 | ||
| median (25th, 75th) | 8 (8, 9) | 9 (8, 9) | |
| Range | 1 to 9 | 3 to 9 | |
| Apgar at 5 minutes* | 0.044 | ||
| median (25th, 75th) | 9 (9, 9) | 9 (9, 9) | |
| Range | 7 to 9 | 7 to 9 |
†
For the morphine group data are summarized for 67 newborns. Data are excluded for one subject who delivered twins.
*
Data are presented using mean±SD or median (25th, 75th) for continuous variables and n (%) for categorical variables. Tubal ligation was compared between groups using the chi-square test and all other characteristics were compared between groups using the rank sum test.