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. 2022 Jan 12;11:e72884. doi: 10.7554/eLife.72884

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© 2022, Stark et al

This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.

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Figure 4. — (A) Wild-type T_m stability data from ProThermDB as a function of organism T_Growth. Dashed black line represents a linear fit (n = 433, R² = 0.43). (B) Fold change (T_m cold/T_m warm) of wild-type protein variants (n = 43, median = 0.81, 95% [0.70, 0.85]). The black vertical line represents no change (i.e., fold change = 1).

Figure 4—source data 1. ProThermDB wild-type protein stability entries.

elife-72884-fig4-data1.csv^{(154.1KB, csv)}

Figure 4—source data 2. ProThermDB wild-type protein stability entries of protein families with more than one reported variant.

elife-72884-fig4-data2.csv^{(4.2KB, csv)}