Figure 3.

Whole-brain vertex-wise analysis of the left and right hemisphere in Freesurfer identifying brain regions whose thickness was associated with (A) age, (B) slow wave activity, (C) speed of processing, and (D) nonverbal intelligence. Statistical maps show regions with positive (red) and negative (blue) correlations between cortical thickness measures and these variables, controlled for sex. The color bars indicate logarithmic scale of p values (−log10). To visually demonstrate widespread changes, significant thresholds were set at p < 0.01, uncorrected. Panels (E) and (F) indicate intersecting brain regions from the conjunction of these three thresholded maps (age, SWA, and speed of processing/nonverbal intelligence). Regions identified in these conjunction analyses were then extracted for further serial mediation analyses.