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. 2022 Jan 8;15:141–152. doi: 10.2147/JIR.S343432

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© 2022 Wu et al.

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Identification of differentially expressed genes (DEGs) that related with CD4⁺ central memory T cell and functional enrichment analysis. (A) The volcano plot of DEGs between oral squamous cell carcinoma (OSCC) groups with high and low CD4⁺ central memory T cell abundance. (B)Gene Ontology (GO) enrichment analysis of DEGs related with CD4⁺ central memory T cell. MF, molecular function; CC, cell component; BP, biological process. (C) Enriched Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways of DEGs related with CD4⁺ central memory T cell. (D) Venn diagram of the overlapped genes between DEGs related with CD4⁺ central memory T cell and prognostic genes in OSCC patients. (E) Cluster analysis for prognostic DEGs related with CD4⁺ central memory T cell OSCC patients from the TCGA cohort. (F) The survival rate of OSCC patients in the TCGA cohort with high and low DEFB1 expression.