Table 2.
Web services for HTVS
| Name | Feature | Developer/maintainer | Website |
|---|---|---|---|
| SwissDock (Grosdidier et al. 2011) | Based on the docking software EADock DSS | Swiss Institute of Bioinformatics | http://www.swissdock.ch |
| Achilles Blind Docking server | Blinding docking server, can use Cloud resources, provide top clusters result preview | Catholic University of Murcia, South East Spain | http://bio-hpc.eu/software/blind-docking-server |
| DOCK Blaster (Irwin et al. 2009) | Based on DOCK software and ZINC database. It provides self-assessment, which estimates the anticipated reliability of the automated screening results using pose fidelity and enrichment | University of California, San Francisco | http://blaster.docking.org |
| Drug Discovery@TACC | Can access to Autodock Vina running on the Lonestar 5 supercomputer at TACC. Ligand libraries were extracted from the ZINC database | Texas Advanced Computing Center, The University of Texas at Austin | https://drugdiscovery.tacc.utexas.edu/#/ |
| Istar (Li et al. 2014) | Based on idock and ZINC database. The results provide binding affinity predicted by RF-Score, putative hydrogen bonds, and supplier information for easy purchase | Chinese University of Hong Kong | http://istar.cse.cuhk.edu.hk/idock/ |
| FINDSITE (Zhou et al. 2013) | Based on FINDSITEcomb. Compound library includes ZINC8, KEGG Compound and BindingDB database | Georgia Institute of Technology | https://sites.gatech.edu/cssb/findsite-comb/ |
| iScreen (Tsai et al. 2011) | Based on PLANTS docking program and traditional Chinese medicine database | China Medical University, Taiwan | http://iscreen.cmu.edu.tw/ |