Table 2.
Drug active ingredient-target gene (common targets of six drugs).
| Gene | Gene ID |
|---|---|
| CASP3 | 836 |
| SOD2 | 6648 |
| NOS3 | 4846 |
| HMOX1 | 3162 |
| MAPK1 | 5594 |
| F2 | 2147 |
| MMP2 | 4313 |
| GSK3B | 2932 |
| MAPK8 | 5599 |
| IL-2 | 3558 |
| PPARG | 5468 |
| NR3C1 | 2908 |
| MAPK14 | 1432 |
| REN | 5972 |
| F3 | 2152 |
| IGF-1 | 3479 |
| BCL2L1 | 598 |
| PARP1 | 142 |
| EGFR | 1956 |
| CASP7 | 840 |
| ALB | 213 |
| CYP19A1 | 1588 |
| PPARA | 5465 |
| GSR | 2936 |
| FABP4 | 2167 |
| IGF-1R | 3480 |
| MMP3 | 4314 |
| MAOA | 4128 |
| NQO1 | 1728 |
| MMP13 | 4322 |
| HSP90AA1 | 3320 |
| CCNA2 | 890 |
| AKR1C3 | 8644 |
| MDM2 | 4193 |
| TGFBR1 | 7046 |
| CALM1 | 801 |
| PGR | 5241 |
| TGFB2 | 7042 |
| CYP2C9 | 1559 |
| ESR1 | 2099 |
| NR3C2 | 4306 |
| KDR | 3791 |
| GSTP1 | 2950 |
| F7 | 2155 |
| AR | 367 |
| NR1I2 | 8856 |
| AURKA | 6790 |
| MAP2K1 | 5604 |
| B2M | 567 |
| CASP1 | 834 |
| HSPA8 | 3312 |
| MAOB | 4129 |
| FGFR1 | 2260 |
| HSP90AB1 | 3326 |
| HMGCR | 3156 |
| JAK2 | 3717 |
| MME | 4311 |
| CTSB | 1508 |
| LCN2 | 3934 |
| HSD11B1 | 3290 |
| SRC | 6714 |
| XIAP | 331 |
| SULT1E1 | 6783 |
| VDR | 7421 |
| GSTA1 | 2938 |
| GCK | 2645 |
| INSR | 3643 |
| CDK2 | 1017 |
| NCOA2 | 10499 |
| S100A9 | 6280 |
| FABP5 | 2171 |
| BMP2 | 650 |
| TEK | 7010 |
| MET | 4233 |
| CDK6 | 1021 |
| CYP2C8 | 1558 |
| CTSK | 1513 |
| PSAP | 5660 |
| THRB | 7068 |
| PDPK1 | 5170 |
| ADAM17 | 6868 |
| KIT | 3815 |
| EPHX2 | 2053 |
| FKBP1A | 2280 |
| MMP12 | 4321 |
| CTSS | 1520 |
| MAPK10 | 5602 |
| FABP3 | 2170 |
| RARA | 5914 |
| MAPKAPK2 | 9261 |
| PIK3R1 | 5295 |
| PDE4D | 5144 |
| LSS | 4047 |
| AKT2 | 208 |
| PIM1 | 5292 |
| AKR1B1 | 231 |
| PLA2G2A | 5320 |
| NR1I3 | 9970 |
| OAT | 4942 |
| DUSP6 | 1848 |
| PGF | 5228 |
| CHEK1 | 1111 |
| ESRRA | 2101 |
| PPIA | 5478 |
| TNNC1 | 7134 |
| AKR1C1 | 1645 |
| GSTM1 | 2944 |
| HCK | 3055 |
| SULT2A1 | 6822 |
| PDK2 | 5164 |
| F10 | 2159 |
| RORA | 6095 |
| NR1H3 | 10062 |
| AKR1C2 | 1646 |
| EIF4E | 1977 |
| BRAF | 673 |
| CA2 | 760 |
| AMD1 | 262 |
| MMP8 | 4317 |
| JAK3 | 3718 |
| NCOA1 | 8648 |
| NR1H4 | 9971 |
| THRA | 7067 |
| PDE4B | 5142 |
| PTPN11 | 5781 |
| GART | 2618 |
| RBP4 | 5950 |
| PDE5A | 8654 |
| BACE1 | 23621 |
| WAS | 7454 |
| GRB2 | 2885 |
| PTPN1 | 5770 |
| PROCR | 10544 |
| SDS | 10993 |
| PPP5C | 5536 |
| PRKCQ | 5588 |
| BCHE | 590 |
| ACADM | 34 |
| DHFR | 1719 |
| FGFR2 | 2263 |
| TTR | 7276 |
| PYGL | 5836 |
| GC | 2638 |
| ANXA5 | 308 |
| CES1 | 1066 |
| LCK | 3932 |
| DPP4 | 1803 |
| FKBP1B | 2281 |
| FABP7 | 2173 |
| FECH | 2235 |
| STS | 412 |
| ELANE | 1991 |
| BAG1 | 573 |
| ERBB4 | 2066 |
| GM2A | 2760 |
| TPX2 | 22974 |
| PLK1 | 5347 |
| TYMS | 7298 |
| DCK | 1633 |
| BHMT | 635 |
| CTNNA1 | 1495 |
| CRABP2 | 1382 |
| ESRRG | 2104 |
| RXRA | 6256 |
| MTAP | 4507 |
| SHBG | 6462 |
| NCOA5 | 57727 |
| PPARD | 5467 |
| ABL1 | 25 |
| TTPA | 7274 |
| FKBP3 | 2287 |
| GRB14 | 2888 |
| PCTP | 58488 |
| CTSF | 8722 |
| ADK | 132 |
| HSD17B1 | 3292 |
| KIF11 | 3832 |
| RFK | 55312 |
| FNTB | 2342 |
| YARS1 | 8565 |
| HNMT | 3176 |
| BCAT2 | 587 |