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Pharmacokinetics parameters calculated using a non-compartmental approach. Maximum concentration (Cmax), the area under the plasma concentration-time curve (AUC) and the clearance (CL) of each tcDNA compound is each shown.
| TcDNA | Cmax (μg/ml) | AUC0–t (h*μg/ml) | AUC0–∞ (h*μg/ml) | CL (ml/h/kg) |
|---|---|---|---|---|
| tcDNA-PO | 695.12 | 276.48 | 276.99 | 180.51 |
| tcDNA-PS | 740.41 | 297.70 | 304.62 | 164.14 |
| Palm-tcDNA-PO | 908.4 | 2029.38 | 2031.06 | 24.62 |
| Palm-tcDNA-PS | 738.42 | 3527.72 | 3627.69 | 13.79 |
