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. 2022 Jan 5;2022:9914778. doi: 10.1155/2022/9914778

Table 1.

Kaplan-Meier plotter was used to analyze the correlation between DOK5 mRNA expression and different clinicopathological factors in gastric cancer.

Clinicopathological factors Overall survival Progression-free survival
N Hazard ratio P value N Hazard ratio P value
Sex
Female 244 1.47 (1.03-2.08) 201 1.46 (1-2.13) 0.051
Male 566 1.28 (1.03-1.59) 437 1.08 (0.85-1.37) 0.55
Stage
1 69 0.63 (0.23-1.71) 0.36 60 0.66 (0.22-2) 0.46
2 145 1.74 (0.93-3.25) 0.077 131 1.5 (0.8-2.79) 0.2
3 319 1.54 (1.15-2.05) 186 1.77 (1.21-2.58) ∗∗
4 152 1.5 (1.02-2.21) 141 1.41 (0.96-2.07) 0.083
Stage T
1 14 14
2 253 1.87 (1.21-2.9) ∗∗ 239 1.66 (1.09-2.54)
3 208 1.27 (0.9-1.8) 0.17 204 1.22 (0.87-1.7) 0.24
4 39 1.59 (0.69-3.62) 0.27 39 2.49 (1.14-5.47)
Stage N
0 76 1.04 (0.44-2.47) 0.92 72 1.21 (0.52-2.8) 0.66
1 232 2.43 (1.57-3.75) ∗∗∗ 222 2.49 (1.64-3.79) ∗∗∗
2 129 1.78 (1.13-2.81) 125 1.56 (1.01-2.41)
3 76 1.88 (1.1-3.22) 76 1.59 (0.93-2.72) 0.085
1+2+3 437 1.97 (1.51-2.58) ∗∗∗ 423 1.9 (1.47-2.47) ∗∗∗
Stage M
0 459 1.8 (1.36-2.39) ∗∗∗ 443 1.71 (1.3-2.24) ∗∗∗
1 58 1.76 (0.98-3.17) 0.0573 56 1.4 (0.77-2.53) 0.27
Lauren classification
Intestinal 336 1.95 (1.41-2.7) ∗∗∗ 263 1.73 (1.2-2.47) ∗∗
Diffuse 248 1.63 (1.16-2.3) ∗∗ 231 1.67 (1.18-2.37) ∗∗
Mixed 33 2.02 (0.72-5.71) 0.1743 28 1.67 (0.6-4.68) 0.32
Differentiation
Poorly differentiated 165 1.19 (0.8-1.78) 0.39 121 1.35 (0.85-2.15) 0.2
Moderately differentiated 67 1.41 (0.73-2.69) 0.3 67 1.58 (0.85-2.96) 0.15
Well differentiated 32 2.45 (1.01-5.95) 5
HER2 status
HER2 negative 532 1.47 (1.17-1.85) ∗∗∗ 408 1.35 (1.04-1.75)
HER2 positive 343 1.16 (0.9-1.51) 0.26 232 1.24 (0.9-1.71) 0.19

P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.001.