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. 2021 Dec 13;7(2):veab104. doi: 10.1093/ve/veab104

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© The Author(s) 2021. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 5. — Structural analysis of spike glycoprotein with recurrent indels. (A) The multiple sequences alignments display of RDT-S-1, RDT-S-2, RDT-S-3, RDT-S-4, RDT-S-5, pos_22289-6, pos_22205+9, pos_22206+9. (B) Tertiary structure of the recurrent indels of spike glycoprotein. B1–B8 are different S protein NTD indels tertiary structure align with template. (B1–B8) del69-70HV (yellow), del145Y (wheat), del156-158EFR (cyan), del210I (forest), del241-243LLA (orange), del242-243LA (splitpea), ins215TDR (light wheat), ins215AAGY (silver) and align with template PDB: 7CWU (green). Deletion or insertion area (red), amino acid change region (pink), corresponding normal area by amino acid change region (blue).