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. 2021 Dec 4;115(1):61–72. doi: 10.1093/ajcn/nqab331

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© The Author(s) 2021. Published by Oxford University Press on behalf of the American Society for Nutrition.

This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)

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Change in the expression of CCR2 on CMs (A), IMs (B), and NCMs (C), in the adherence of monocyte subsets to HUVECs (D), and in the trans-endothelial migration of monocyte subsets through HUVECs (E) after consuming L, M, and H for 4 wk in fasted adults at risk of cardiometabolic disease. Labeled means without a common letter differ, P < 0.05. *Significant change from baseline, P < 0.05. Data are mean ± SEM. CCR2, n = 23. Adherence and migration indexes, n = 6. CCR2, C-C chemokine receptor type 2; CM, classical monocyte; H, high-dose spice diet; HUVEC, human umbilical vein endothelial cell; IM, intermediate monocyte; L, low-dose spice diet; M, medium-dose spice diet; MFI, mean fluorescence intensity; NCM, nonclassical monocyte.