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. 2022 Jan 5;6(1):ytab534. doi: 10.1093/ehjcr/ytab534
Time Event
30 April First dose of coronavirus disease 2019 (COVID-19) vaccine.
21 May Second dose of COVID-19 vaccine.
22 May Fever, headache, appetite loss, general malaise, and shoulder stiffness, which was treated with acetaminophen.
23 May Onset of chest pain and persistent fever, headache, and appetite loss.
24 May The patient visited outpatient clinic and was admitted to the high care unit; elevated markers of myocardial damage such as high-sensitivity troponin I, creatine kinase, C-reactive protein, and diffuse ST-segment elevation on electrocardiogram (ECG). An urgent coronary angiogram showed no significant stenosis. Anti-inflammatory drugs were started and the patient’s symptoms improved.
25–26 May The patient was haemodynamically stable and asymptomatic. A subsequent ECG showed partial resolution of the ST changes and a trend towards improvement.
27 May The patient was discharged in order to perform cardiac magnetic resonance imaging (MRI).
31 May The patient visited the outpatient clinic with mild general fatigue. Cardiac MRI showed myocardial late gadolinium enhancement with epicardial predominance in the antero-septal, inferior and lateral walls of the basal segment and apex, which were consistent with acute myocarditis.
3 June The patient recovered and returned to work.
14 June Despite no deterioration in cardiac function, the patient complained of appetite loss and fatigue on exertion, was diagnosed as post-vaccination syndrome and was absent from work for a month.
12 July The patient recovered to some extent and returned to work.
29 July The patient complained of general malaise and sleep disturbance, was diagnosed as depressive state and is currently on leave.