Figure 1.

Urinary 11-dehydrothromboxane B2 (TXB2) levels in African American and European American men and their association with prostate cancer and National Comprehensive Cancer Network (NCCN) risk scores. A) Urinary TXB2 levels in cases and controls shown as a continuous measure, stratified by race. B) Bar charts show distribution of cases and controls stratified into African American and European American men across TXB2 quartiles (Q). Q cutoff points originate from the combined control groups and are 0.35, 0.505, and 0.738 ng TXB2/mg creatinine. C) Shown are urinary TXB2 levels across 4 NCCN risk score categories. Two-sided Mann-Whitney (A), χ² (B), and Kruskal-Wallis (C) tests were applied for statistical significance testing. The error bars in (A) and (C) represent the 95% confidence interval.