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Elisa-based comparative binding analysis of C6-loaded targeted and non targeted NP (C6-TNP-1-4, and C6-NP-0) with ACE2. Histograms represent the best fitting of the association processes. Affinity results are expressed as difference in response of relative fluorescent units (RFU). Data shown are representative of three independent experiments. (∗) and (∗∗) significantly (∗∗p < 0.01 and ∗p < 0.05 vs. C6-NP-0, n = 4) by one-way ANOVA and post-hoc Dunnett's test.
