Table 2.
Average Diameter, Polydispersity Index (PDI), percentage of Encapsulation Efficiency (EE %), RDV Loading Capacity (LC %), and Yield of Production (YP %) of RDV-loaded and unloaded NP (RDV-TNP-1, and TNP-1E, respectively), and Rho-loaded NP (Rho-NP-0 and Rho-NP-1). Data are mean ± SD, n = 3.
Batch | Mean diameter (nm) | PDI | EE (%) | LC (%) | YP (%) |
---|---|---|---|---|---|
RDV-TNP-1 | 101.27 ± 5.39 | 0.105 ± 0.03 | 51.35 ± 1.37 | 1.03 ± 0.03 | 73.17 ± 2.02 |
TNP-1E∗ | 111.29 ± 7.47 | 0.104 ± 0.03 | – | – | 69.67 ± 1.15 |
Rho-NP-0 | 130.12 ± 7.28 | 0.112 ± 0.02 | 34.89 ± 5.43 | 0.017 ± 0.003 | 63.47 ± 4.39 |
Rho-TNP-1 | 129.68 ± 5.87 | 0.136 ± 0.04 | 29.19 ± 0.75 | 0.015 ± 0.001 | 61.13 ± 1.23 |
Each value is the mean ± SD of triplicate determinations. ∗E indicates “empty” NP.