Table 2.
Test sensitivity, localization probability, and implied marginal sensitivity of multi-cancer test for selected stage I-III cancers based on Liu et al. The implied mortality reduction among cases detected early corresponding to a 10% mortality reduction associated with single-occasion screening is also shown.
| Tissue of origin | Test sensitivity, % | Localization probability, % | Marginal sensitivity, % | Mortality reduction, % |
|---|---|---|---|---|
| Breast | 64 | 96 | 61 | 16 |
| Colorectal | 74 | 97 | 72 | 14 |
| Lung | 59 | 92 | 54 | 18 |
| Ovary | 67 | 96 | 64 | 16 |
| Pancreas | 78 | 79 | 62 | 16 |
| Liver | 68 | 72 | 49 | 20 |