Table 3.
Expected number of women potentially exposed to unnecessary confirmation tests (EUC), expected cancers detected (CD), expected lives saved (LS), and harm-benefit tradeoffs EUC/CD and EUC/LS per 1,000 women tested with a multi-cancer test for breast, colorectal, liver, lung, pancreatic, and ovary cancers assuming 99% specificity and a common 10% mortality reduction associated with screening for each cancer.
Screening age, y | EUC, n | CD, n | LS, n | EUC/CD | EUC/LS |
---|---|---|---|---|---|
50 | 10.4 | 11.7 | 0.7 | 0.9 | 14.2 |
60 | 11.0 | 22.1 | 1.9 | 0.5 | 5.7 |
70 | 11.6 | 33.1 | 3.9 | 0.4 | 3.0 |