Table 3.
Presence of F nucleatum subspecies in colorectal cancer tissue and CRC-specific survival.
|
F nucleatum subsp animalis |
cases (n) |
events (n) |
aHR (95% CI) | bHR (95% CI) |
|---|---|---|---|---|
| Negative | 1196 | 224 | 1.00 (reference) | 1.00 (reference) |
| animalis | 80 | 20 | 2.16 (1.34-3.47) | 1.75 (0.99- 3.10) |
| p-value | 0.0016 | 0.056 | ||
| vincentii + nucleatum | 40 | 6 | 1.07 (0.48-2.43) | 1.02 (0.42-2.51) |
| p-value | 0.86 | 0.96 |
HR = Hazard Ratio, CI = Confidence Interval
a
multivariable analysis adjusted for sex, age at diagnosis, tumor site, hypermutation status, tumor burden, mutations in POLE, TP53, and ERBB3, and MSI status
b
multivariable analysis adjusted for sex, age at diagnosis, tumor site, hypermutation status, tumor burden, mutations in POLE, TP53, and ERBB3, and MSI status, and tumor stage