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. Author manuscript; available in PMC: 2023 Jan 1.
Published in final edited form as: Mech Ageing Dev. 2021 Nov 12;201:111597. doi: 10.1016/j.mad.2021.111597

Table 1.

ANOVA of developmental and metabòlic traits.

Source Nparm DF Sum of Squares F ratio Prob > F

Age 1 1 3862.45 1335.83 <0.0001
Body weight Sex 1 1 349.98 121.04 <0.0001
Treatment 1 1 11.41 3.94 0.049
Treatment*Sex 1 1 0.58 0.20 0.654
Age 1 1 45.75 178.03 <0.0001
Sex 1 1 26.86 104.50 <0.0001
Food consumption Treatment 1 1 2.32 9.04 0.003
Treatment*Sex 1 1 0.01 0.05 0.818
Sex 1 1 1.27 13.44 <0.001
Tail length (70 days) Treatment 1 1 1.47 15.54 <0.001
Treatment*Sex 1 1 0.03 0.36 0.551
Sex 1 1 0.00 0.00 0.966
Tail length ADM Treatment 1 1 0.00 9.17 0.003
Treatment*Sex 1 1 0.00 0.13 0.720
Sex 1 1 2552979.97 51.70 <0.0001
Treatment 1 1 1600761.36 32.42 <0.0001
Fasting 1 1 10131049.51 205.18 <0.0001
IGF1 conc. (ng/mI) Treatment*Sex 1 1 27795.97 0.56 0.456
Fasting*Sex 1 1 91706.42 1.86 0.177
Fasting*Treatment 1 1 1192233.28 24.15 <0.0001
Fasting*Treatment*Sex 1 1 48797.32 0.99 0.324
Sex 1 1 0.24 6.58 0.012
Treatment 1 1 0.35 9.56 0.003
Fasting 1 1 0.02 0.65 0.422
IGF1 variation Treatment*Sex 1 1 0.01 0.31 0.579
Fasting*Sex 1 1 0.00 0.00 0.997
Fasting*Treatment 1 1 0.00 0.01 0.928
Fasting*Treatment*Sex 1 1 0.00 0.01 0.920
Sex 1 1 11316.80 11.45 0.001
GTT basal glucose Treatment 1 1 19211.00 19.43 <0.0001
Treatment*Sex 1 1 4210.76 4.26 0.041
Sex 1 1 64316.63 42.11 <.0001
GTT AUC Treatment 1 1 17732.97 11.61 <.0001
Treatment*Sex 1 1 2859.27 1.87 0.174
Sex 1 1 33028.35 60.06 <0.0001
ITT basal glucose Treatment 1 1 797.71 1.45 0.231
Treatment*Sex 1 1 0.04 0.00 0.993
Sex 1 1 112062.23 112.27 <.0001
ITT AUC Treatment 1 1 570.57 0.57 0.451
Treatment*Sex 1 1 4.90 0.00 0.944
Sex 1 1 0.69 20.31 <0001
Treatment 1 1 0.04 1.30 0.259
Fasting 1 1 0.71 20.63 <0001
Insulin level Treatment*Sex 1 1 0.17 4.92 0.029
Fasting*Sex 1 1 0.36 10.46 0.002
Fasting*Treatment 1 1 0.01 0.44 0.511
Fasting*Treatment*Sex 1 1 0.06 1.74 0.191
Sex 1 1 0.01 10.95 0.002
QUICKI Treatment 1 1 0.00 0.05 0.825
Treatment*Sex 1 1 0.01 10.01 0.003
Sex 1 1 4.87 0.98 0.326
Treatment 1 1 4.74 0.95 0.333
Fasting 1 1 338.87 68.00 <0.0001
Adiponectin level Treatment*Sex 1 1 60.92 12.22 0.001
Fasting*Sex 1 1 0.16 0.03 0.856
Fasting*Treatment 1 1 1.31 0.26 0.610
Fasting*Treatment*Sex 1 1 31.32 6.28 0.014