Skip to main content
. Author manuscript; available in PMC: 2022 Jul 15.
Published in final edited form as: J Immunol. 2021 Dec 10;208(2):444–453. doi: 10.4049/jimmunol.2001389

Figure 5.

Figure 5.

Cell-mediated immune responses in LPS-treated WT versus SAMHD1 KO mice at 14 dpi. Splenocytes from WT (n=18) and SAMHD1 KO (n=16) mice were subjected to flow cytometry, evaluating the percentage of IFNγ+ cells in (A) NK cells (CD3-NK1.1+); (B) CD4 T cells (CD3+CD4+) and (C) CD8+ T cells (CD3+CD8+). Left panels correspond to the full cohort, whereas middle and right panels partitioned the data into males and females, respectively. For all panels, each data point corresponds to a mouse. The data were pooled from 3 independent cohorts of WT and SAMHD1 KO mice. Each experiment consisted of WT (n=5–7) and SAMHD1 KO (n=5–6) mice. Data were analyzed using a 2-tailed unpaired Student’s t-test. *, p<0.05, ***, p<0.001; NS, not significant (p>0.05).