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. 2022 Jan 12;12:599. doi: 10.1038/s41598-021-04510-2

Table 2.

Association between MAGE-A11 expressions (staining intensity and H-score) and clinic-pathological parameters of BC cases (P-value, Pearson’s chi-square test).

Patients and tumor characteristics Total samples N (%) Nuclear expression of MAGE-A11 Cytoplasmic expression of MAGE-A11
Staining Intensity H-score Staining Intensity H-score
Median age
Years
 ≤ 67 108 (51) 0.079 0.075 0.638 0.932
 > 67 105 (49)
Gender
Male 170 (80) 0.708 0.839 0.603 0.372
Female 43 (20)
Mean tumor size (cm)
 ≤ 2.5 134 (63) 0.741 0.789 0.139 0.125
 > 2.5 79 (37)
Histological grade
Low 94 (44) 0.349 0.554  < 0.0001  < 0.0001
High 119 (56)
pT stage
pTa 87 (40.8) 0.219 0.579  < 0.0001  < 0.0001
pT1 95 (44.6)
pT2 31 (14.6)
pT3 0 (0)
pT4 0 (0)
Lamina propria involvement
Involved 126 (59) 0.292 0.954  < 0.0001  < 0.0001
None 87 (41)
Muscularis invasion
Involved 31 (14.6) 0.14 0.339 0.334 0.684
None 182 (85.4)
Lamina propria/muscularis involvement (L/M)
L − /M- 87 (40.8) 0.219 0.579 0.0001  < 0.0001
L + /M- 95 (44.6)
L + /M +  31 (41.6)
Recurrence
Present 57 (27) 0.577 0.692 0.203 0.695
Absent 156 (73)
Distant metastasis
Present 33 (15.5) 0.262 0.49 0.097 0.932
Absent 180 (84.5)

Bold numbers represent significant p-values.