. 2022 Jan 12;12:599. doi: 10.1038/s41598-021-04510-2

Table 6.

Association between nuclear and cytoplasmic MAGE-A6 (A6)/MAGE-A11 (A11) phenotypes and clinicopathological parameters in BC cases (P‐value, one‐way ANOVA and Tukey s post hoc).

Tumor characteristic	Nuclear phenotypes	P value	Cytoplasmic phenotypes	P value
Tumor size (cm)	A6^l/A11^l & A6^h/A11^h A6^l/A11^h & A6^h/A11^h	0.004 0.046	A6^l/A11^l & A6^h/A11^h	0.02
Histological grade	A6^l/A11^l & A6^h/A11^l A6^l/A11^l & A6^h/A11^h A6^h/A11^l & A6^l/A11^h A6^l/A11^h& A6^h/A11^h	< 0.0001 < 0.0001 < 0.0001 0.002	A6^l/A11^l & A6^h/A11^h A6^h/A11^l & A6^h/A11^h A6^l/A11^h & A6^h/A11^h	< 0.0001 0.003 0.006
pT stage	A6^l/A11^l & A6^h/A11^l A6^l/A11^l & A6^h/A11^h	0.002 0.007	A6^l/A11^l & A6^h/A11^h	0.002
Lamina propria	A6^l/A11^l & A6^h/A11^l A6^l/A11^l & A6^h/A11^h A6^l/A11^h & A6^h/A11^h	< 0.0001 0.001 0.036	A6^l/A11^l & A6^h/A11^h A6^h/A11^l & A6^h/A11^h A6^l/A11^h & A6^h/A11^h	< 0.0001 < 0.0001 0.036
Lamina propria/muscularis	A6^l/A11^l & A6^h/A11^l A6^l/A11^l & A6^h/A11^h	0.001 0.002	A6^l/A11^l & A6^h/A11^h A6^h/A11^l & A6^h/A11^h	< 0.0001 0.004

Tumor characteristic

Nuclear phenotypes

P value

Cytoplasmic phenotypes

P value

Tumor size (cm)

A6^l/A11^l & A6^h/A11^h

A6^l/A11^h & A6^h/A11^h

0.004

0.046

A6^l/A11^l & A6^h/A11^h

0.02

Histological grade

A6^l/A11^l & A6^h/A11^l

A6^l/A11^l & A6^h/A11^h

A6^h/A11^l & A6^l/A11^h

A6^l/A11^h& A6^h/A11^h

< 0.0001

0.002

A6^l/A11^l & A6^h/A11^h

A6^h/A11^l & A6^h/A11^h

A6^l/A11^h & A6^h/A11^h

< 0.0001

0.003

0.006

pT stage

A6^l/A11^l & A6^h/A11^l

A6^l/A11^l & A6^h/A11^h

0.002

0.007

A6^l/A11^l & A6^h/A11^h

0.002

Lamina propria

A6^l/A11^l & A6^h/A11^l

A6^l/A11^l & A6^h/A11^h

A6^l/A11^h & A6^h/A11^h

< 0.0001

0.001

0.036

A6^l/A11^l & A6^h/A11^h

A6^h/A11^l & A6^h/A11^h

A6^l/A11^h & A6^h/A11^h

< 0.0001

0.036

Lamina propria/muscularis

A6^l/A11^l & A6^h/A11^l

A6^l/A11^l & A6^h/A11^h

0.001

0.002

A6^l/A11^l & A6^h/A11^h

A6^h/A11^l & A6^h/A11^h

< 0.0001

0.004

It should be noted that only p-value of phenotypes that were significant with clinicopathological parameters were shown.