Table 1.
Demographic and Clinical Characteristics of Study Participants (n = 41).
| Characteristics |
Low Co-Occurring symptom
Group (n = 22) |
High Co-Occurring Symptom
Group (n = 19) |
p-Value* |
|---|---|---|---|
| Sex (male), n (%) | 13 (59) | 12 (63) | |
| Stage, n (%) | |||
| II | 7 (32) | 3 (16) | |
| III | 15 (68) | 16 (84) | |
| Race, n (%) | |||
| Non-Hispanic White | 9 (41) | 10 (54) | |
| Hispanic White | 10 (45) | 7 (38) | |
| African American | 3 (14) | 1 (4) | |
| Asian | 0 | 1 (4) | |
| Marital status, n (%) | |||
| Married/partnered | 16 (72) | 10 (54) | |
| Single/divorced | 6 (28) | 9 (46) | |
| Occupation, n (%) | |||
| Working | 13 (59) | 11 (58) | |
| Retired | 6 (27) | 5 (26) | |
| Disability | 3 (14) | 4 (16) | |
| Pretreatment symptoms exceeding cut-point, n (%) | |||
| All low | 22 (100) | ||
| Fatigue + SD + Depression | 9 (46) | ||
| Fatigue + SD | 7 (38) | ||
| Fatigue + Depression | 3 (16) | ||
| Raw symptom scores | |||
| PROMIS-F; Median (IQR) | 12.0 (10, 16) | 23.0 (21,26) | 0.001 |
| PROMIS-SD; Median (IQR) | 17.5 (12, 22) | 32.0 (29, 36) | 0.001 |
| HAM-D17; Median (IQR) | 6.0 (1,12.5) | 15.5 (5, 19) | 0.06 |
| Age, Median (IQR) | 58.0 (52, 72) | 60.0 (50,60) | 0.80 |
| HgB, Median (IQR) | 13.3 (11.3, 14) | 11.8 (11.2, 13.7) | 0.84 |
| BMI, Median (IQR) | 25.5 (21.9, 27.7) | 26.7 (22.9, 31.8) | 0.36 |
Note. BMI = body mass index; CRT = neoadjuvant chemotherapy and radiation therapy; F = fatigue; HAM-D = Hamilton Rating Scale for Depression; Hgb = hemoglobin levels; IQR = interquartile range; PROMIS = Patient-Reported Outcome Measures Information System; SD = sleep disturbance. Possible raw score ranges for the PROMIS-F, PROMIS-SD, and HAM-D17 are 7–35, 7–35, and 0–50, respectively.
*p-value for two-tailed Fisher’s Exact or Mann-Whitney test.