Table 2.

Comparison of Alpha Diversity Indexes Between Participants Who Had Developed High Co-Occurring Symptoms and Those Who Developed Low Co-Occurring Symptoms Before CRT for Rectal Cancer (n = 41).

Diversity Index	Low Co-Occurring Symptom Group (n = 22)	High Co-Occurring Symptom Group (n = 19)	p-Value*
	Median (IQR)	Median (IQR)
Shannon	6.66	6.49	0.87
Observed OTU	157.5	158	0.60
Pielou’s Evenness	0.91	0.89	0.28
Faith’s PD	12.47	12.28	0.89

Note. CRT = chemotherapy and radiation therapy; HAM-D = Hamilton Rating Scale for Depression; OTU = operational taxonomic units, PD = phylogenetic diversity; PROMIS-F = Patient-Reported Outcome Measures Information System-fatigue; PROMIS-SD = Patient-Reported Outcome Measures Information System-sleep disturbance.

*p-value for two-tailed Kruskal-Wallis test.