Table 1.

Oxidative Stress Serum Parameters in Patients With Major Depressive Disorder

Frequent parameters	Indicator
8-Hydroxydesoxyguanosin	One of the most recognized biomarkers of oxidative DNA damage; generated after repairement of damage induced by Reactive oxygen Species (ROS); can be determined in urine and blood
F2-Isoprostanes	Inflammation; arachidonic acid peroxidation; can be determined in urine and blood
Peroxidase
Malondialdehyde	Lipid peroxidation; serum
Superoxide dismutase	Antioxidant; determination in blood
Glutathione	Antioxidant; determination in blood
Glutathione peroxidase	Antioxidant damage by H2O2
Nitric oxide	Accelerated production of superoxide anion
Xanthine oxidase	Production of superoxide and H2O2 determination in blood