Table 2.

Effects of dietary intervention on lipid profiles and levels of glucose, insulin, hs-CRP and 8-epi-PGF_2α at baseline and 12-week follow-up

(Mean values with their standard errors of the mean)

	Legume-enriched diet (n=160)		Usual diet (n=223)		P
	Mean	sem	Mean	sem
LDL-cholesterol (mg/dl)
Before†	111·0	2·44	114·6	2·60	0·918
After†	108·0	2·61	113·1	2·50	0·196
Change	–2·99	2·03	–1·50	2·17	0·616
HDL-cholesterol (mg/dl)
Before†	45·6	0·98	43·7	0·78	0·165
After†	48·1	0·88**	44·8	0·80	0·003
Change	2·48	0·76	1·55	0·63	0·342
Glucose (mg/dl)
Before†	97·4	1·82	99·3	1·78	0·531
After†	93·8	2·65**	97·9	1·99	0·039
Change	–3·59	1·94	–1·41	1·63	0·388
Insulin (μIU/ml)
Before†	11·8	0·54	10·8	0·36	0·446
After†	9·17	1·07**	10·6	0·52	< 0·001
Change	–2·58	0·96	–0·17	0·53	0·020
NEFA (μEq/l)
Before†	532·4	1·8·0	524·9	17·3	0·572
After†	507·5	20·1	503·0	16·3	0·952
Change	–24·8	18·8	–21·9	17·7	0·911
hs-CRP (mg/dl)
Before†	1·97	0·08	2·09	0·09	0·707
After†	1·89	0·09	2·09	0·11	0·854
Change	–0·19	0·07	0·00	0·10	0·132
8-epi-PGF2α (pg/mg creatinine)
Before†	1330·5	81·9	1346·4	66·7	0·504
After†	1216·6	80·7*	1299·2	65·5	0·077
Change	–56·3	75·7	–36·7	65·9	0·844

hs-CRP, high-sensitivity C-reactive protein.

*P < 0·05, **P < 0.001 compared with baseline values in each diet group as tested using paired t test. P-values derived from independent t test.

^†Tested using logarithmic transformation.