. 2021 Mar 24;54(1):65–74. doi: 10.4143/crt.2021.142

Table 3.

Univariate and multivariate analysis in all patients

	Overall survival				Disease-free survival				Local control rate				Regional control		Distant metastasis-free survival

	10-Year	p-value^a)	HR^b)	p-value^b)	10-Year	p-value^a)	HR^b)	p-value^b)	10-Year	p-value^a)	HR^b)	p-value^b)	10-Year	p-value^a)	10-Year	p-value^a)	HR^b)	p-value^b)
Age (yr)

< 60	82.8	0.010	3.265	0.031	30.4	0.646	-	-	48.9	0.277	-	-	85.6	0.999	63.4	0.289	-	-

≥ 60	61.2				31.8				50.0				100		73.1

Sex

Male	81.4	0.284	-	-	34.2	0.874	-	-	55.1	0.858	-	-	88.8	0.853	60.2	0.923	-	-

Female	79.2				27.0				44.2				84.9		67.5

ECOG

0	79.4	0.113	-	-	33.2	0.251	-	-	55.2	0.095	1.104	0.813	89.2	0.154	63.5	0.370	-	-

1–2	88.9				NR				NR				68.6		62.2

Tumor location

Supratentorial	76.1	0.186	-	-	31.6	0.723	-	-	52.1	0.317	-	-	85.6	0.947	58.3	0.047	0.541	0.154

Infratentorial	90.4				32.7				49.1				90.2		76.7

Tumor size (cm)

< 5	88.6	0.102	-	-	39.5	0.621	-	-	60.1	0.581	-	-	91.7	0.739	75.8	0.144	-	-

≥ 5	72.8				27.3				42.9				82.0		54.2

Surgical extent

STR	74.9	0.058	2.218	0.109	12.1	0.0007	2.063	0.014	15.6	0.0003	2.368	0.001	85.1	0.778	59.3	0.339	-	-

GTR	83.4				42.2				65.6				87.9		65.2

PORT

PORT	87.6	0.762	-	-	39.6	0.0001	0.247	< 0.001	63.4	0.0001	0.339	< 0.001	82.0	0.439	53.3	0.191	-	-

Surgery only	75.1				17.4				27.9				93.9		79.5

WHO grade

III	74.9	0.123	-	-	27.7	0.504	-	-	53.2	0.355	-	-	84.3	0.359	49.6	0.020	2.010	0.029

II	84.7				35.3				49.2				89.8		75.7

Ki-67 (%)

< 10	86.0	0.507	-	-	31.1	0.049	1.765	0.043	41.2	0.903	-	-	85.2	0.663	66.5	0.460	-	-

≥ 10	85.6				NR				50.9				77.5		64.7

ECOG, Eastern Cooperative Oncology Group; GTR, gross total resection; HR, hazard ratio; PORT, postoperative radiotherapy; STR, subtotal resection; WHO, World Health Organization.

^a)

Log-rank test,

^b)

Cox proportional hazard model.