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. 2022 Jan 5;2022:2930310. doi: 10.1155/2022/2930310

Figure 2.

Figure 2

(a) The mutation frequency of 23 m6A regulators in 561 LUAD patients from the TCGA cohort. Each column represented individual patients. The upper barplot showed TMB; the number on the right indicated the mutation frequency in each regulator. The right barplot showed the proportion of each variant type. The stacked barplot below showed a fraction of conversions in each sample. (b) The CNV variation frequency of m6A regulators. The height of the column represented the alteration frequency. The deletion frequency, blue dot; the amplification frequency, red dot. (c) The location of CNV alteration of m6A regulators on 23 chromosomes. (d) The expression of 23 m6A regulators between normal tissues and LUAD tissues. Tumor, red; normal, blue. The upper and lower ends of the boxes represented the interquartile range of values. The lines in the boxes represented median value, and black dots showed outliers. The asterisks represented the statistical P value (P < 0.05; ∗∗P < 0.01; ∗∗∗P < 0.001).