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. 2021 Dec;9(24):1798. doi: 10.21037/atm-21-6556

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2021 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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MiR-499a-5p was overexpressed in PC tissue and cell lines. (A) MiR-499a-5p under the assessment of qRT-PCR analysis involving 45 paired PC tissues. (B) MiR-499a-5p level in PC patient with 5-FU resistance vs. those with 5-FU sensitivity. (C) MiR-499a-5p level in PC cells vs. control cells under qRT-PCR. (D) MiR-499a-5p expression in PANC1/FR (5-FU resistant) and naive PANC1 cells. *, P<0.05; **, P<0.01; ***, P<0.001. PC, pancreatic cancer; qRT-PCR, real-time quantitative polymerase chain reaction.