Table 1. Association between miR-499a-5p expression and clinicopathologic characteristics of PC patients in the study cohort.
Characteristics | No. of patients | P valuea | |
---|---|---|---|
Low (n=23) | High (n=22) | ||
Gender | 0.903 | ||
Female | 9 | 9 | |
Male | 14 | 13 | |
Age (years) | 0.445 | ||
<60 | 5 | 7 | |
≥60 | 18 | 15 | |
Tumor location | 0.626 | ||
Rectum | 10 | 8 | |
Colon | 13 | 14 | |
Differentiation grade | 0.815 | ||
Well + moderate | 16 | 16 | |
Poor | 7 | 6 | |
Tumor size (cm) | 0.047* | ||
<5 | 13 | 6 | |
≥5 | 10 | 16 | |
Local invasion | 0.372 | ||
pT1-T2 | 15 | 17 | |
pT3-pT4 | 8 | 5 | |
Lymph node metastasis | 0.048* | ||
Negative | 18 | 11 | |
Positive | 5 | 11 | |
TNM stage | 0.003* | ||
I + II | 14 | 4 | |
III | 9 | 18 |
a, Pearson chi-square test was used for comparison between subgroups; *, statistical significance.