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. 2021 Dec;9(24):1777. doi: 10.21037/atm-21-6301

Figure 7.

Figure 7

The preferred prescription suppressed GC cells proliferation and induced cell apoptosis. (A) MTT assay showing a concentration-dependent effect of the preferred prescription on the viability of AGS, HGC27, MKN28, and SGC7901 cells. (B) The inhibitory effect of the preferred prescription on the tumor growth of nude mouse xenograft models. The weights of the tumors (C), and the weights of the nude mice (D) were monitored (n=5). (E,F) Flow cytometry depicting cell apoptosis of GC cells treated with different concentrations of the preferred prescription. (G-I) The pro- and anti-apoptotic proteins were detected in MKN28 cells treated with different concentrations of the preferred prescription by western blotting. (J-K) The pro- and antiapoptotic proteins were detected in tumors of nude mouse xenograft models (n=5) by western blotting; *, P<0.05, **, P<0.01, ***, P<0.001, ****, P<0.0001 vs. Control. GC, gastric cancer; MTT, 3-(4,5-Dimethyl-2-thizolyl)-2,5- diphenyltetrazolium bromide.