Table 1:

Description of hospital-based strategies within the simulation model

	Individuals in the model who are eligible for this intervention	Definition	Effect in the model
Addiction consult service	Overdose, skin and soft tissue infections, infective endocarditis, or a combination of these	People who receive an addiction consult benefit from addiction counselling, offer of methadone or buprenorphine, referral and linkage to outpatient addiction treatment including all forms of medication for opioid use disorder and non-medication treatments	Change probability of linkage to outpatient addiction care, change probability of linkage to outpatient medication for opioid use disorder, or change probability of transitioning between injection frequency states
Initiation of medication for opioid use disorder (eg, buprenorphine)	Overdose, skin and soft tissue infections, infective endocarditis, or a combination of these	The medication for opioid use disorder strategy models the impact of non-addiction trained providers prescribing buprenorphine; patients might receive short-term in-hospital methadone (any physician or advance practice provider can prescribe for hospitalised patients), but methadone is not extended beyond hospitalisation	Change probability of linkage to outpatient medication for opioid use disorder, change probability of transitioning between injection frequency states