Table 2.

Adjusted odds ratio for weighted genetic risk scores (w‐GRS) and haplogroups for insulin use

	Unadjusted	Model 1
Haplogroup
Non‐D4	1	1
D4	0.41 (0.18‐0.92)*	0.41 (0.17‐0.97)*
w‐GRS
wT‐GRS	1.08 (0.48‐2.46)	1.13 (0.48‐2.66)
wβ‐GRS	1.32 (0.59‐2.96)	1.30 (0.61‐3.04)
wR‐GRS	0.61 (0.10‐3.72)	0.80 (0.12‐5.47)
wT‐GRS
Low	1	1
Medium	0.78 (0.48‐1.28)	0.78 (0.46‐1.33)
High	0.91 (056‐1.47)	0.96 (0.58‐1.60)

Values represent odd ratios and confidence intervals.

Model 1 adjusted for sex, age and duration of diabetes.

*P < 0.05.

wT‐GRS, weighted total genetic risk score; wβ‐GRS, weighted β‐cell function‐related genetic risk score; wR‐GRS, weighted insulin resistance and obesity‐related genetic risk score.