Table 4.
Spearman correlations between glutamate and GABA concentrations (absolute and relative) in rACC and thalamus.
| N (rACC/thalamus) | rACC | THALAMUS | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Absolute | Relative | Absolute | Relative | ||||||
| r | P | r | P | r | P | r | P | ||
| Across subjects | 108/116 | 0.2899 | 0.0023 | 0.2232 | 0.0202 | 0.3036 | <0.001 | 0.3512 | <0.001 |
| FM | 68/74 | 0.3248 | 0.0069 | 0.3541 | 0.0031 | 0.2967 | 0.0103 | 0.3461 | 0.0025 |
| HC | 40/42 | 0.2387 | 0.1380 | −0.0479 | 0.7694 | 0.3008 | 0.0529 | 0.3381 | 0.0285 |
| HAB | 65/66 | 0.4634 | <0.001 | 0.5289 | <0.001 | 0.3378 | 0.0055 | 0.3090 | 0.0116 |
| MLAB | 43/50 | −0.0107 | 0.9460 | −0.2985 | 0.0518 | 0.2122 | 0.1390 | 0.4018 | 0.0038 |
| FM HAB | 44/45 | 0.4086 | 0.0059 | 0.5579 | <0.001 | 0.3069 | 0.0403 | 0.3359 | 0.0241 |
| FM MLAB | 24/29 | 0.0636 | 0.7678 | −0.2039 | 0.3392 | 0.1394 | 0.4707 | 0.3303 | 0.0801 |
| HC HAB | 21/21 | 0.5618 | 0.0080 | 0.5215 | 0.0153 | 0.3355 | 0.1371 | 0.1886 | 0.4129 |
| HC MLAB | 19/21 | −0.1053 | 0.6680 | −0.5035 | 0.0280 | 0.2706 | 0.2355 | 0.4518 | 0.0398 |
Correlations, significant at the conventional P < 0.05, are presented in bold.
FM, fibromyalgia; HAB, high affinity binders; HC, healthy controls; MLAB, mixed/low affinity binders; rACC, rostral anterior cingulate cortex; Absolute, absolute compound concentrations; Relative, relative compound concentrations.