Table 1. Demographic and Clinical Characteristics of Participants Randomized to Antibiotics by Appendectomy Status at 30 Days.
| Characteristic | No. (%)a | ||
|---|---|---|---|
| Overall (n = 776) | Underwent appendectomy within 30 d | ||
| Yes (n = 154) | No (n = 581) | ||
| Age, y | |||
| Mean (SD) | 38.3 (13.4) | 38.8 (13.7) | 38.0 (13.2) |
| ≥50 | 150 (19) | 32 (21) | 104 (18) |
| <50 | 626 (81) | 122 (79) | 477 (82) |
| Sex | |||
| Female | 286 (37) | 61 (40) | 211 (36) |
| Male | 490 (63) | 93 (60) | 370 (64) |
| Race | |||
| American Indian or Alaska Native | 13 (2) | 4 (3) | 6 (1) |
| Asian | 39 (5) | 10 (6) | 29 (5) |
| Black | 75 (10) | 16 (11) | 58 (10) |
| Native Hawaiian or Pacific Islander | 4 (1) | 1 (1) | 2 (<1) |
| White | 461 (60) | 79 (52) | 359 (63) |
| Multiple or otherb | 176 (23) | 43 (28) | 120 (21) |
| Hispanic | |||
| No | 414 (53) | 77 (50) | 321 (55) |
| Yes | 362 (47) | 77 (50) | 260 (45) |
| Preferred language | |||
| English | 538 (69) | 103 (67) | 410 (71) |
| Spanish | 238 (31) | 51 (33) | 171 (29) |
| Health literacy help | |||
| Never or rarely | 608 (81) | 115 (76) | 466 (83) |
| Sometimes or more | 141 (19) | 36 (24) | 93 (17) |
| Worried about bills | |||
| No | 217 (29) | 37 (24) | 168 (30) |
| Yes | 545 (72) | 116 (76) | 402 (71) |
| Below federal poverty level or Medicaid beneficiary | |||
| No | 315 (54) | 54 (47) | 251 (57) |
| Yes | 273 (46) | 61 (53) | 190 (43) |
| Modified Charlson comorbidity score, mean (SD) | 0.2 (0.5) | 0.3 (0.7) | 0.2 (0.5) |
| BMI | |||
| <25 | 178 (30) | 35 (25) | 138 (32) |
| 25-<30 | 198 (33) | 51 (36) | 132 (31) |
| 30-<35 | 128 (21) | 35 (25) | 85 (20) |
| ≥35 | 98 (16) | 19 (14) | 77 (18) |
| Alvarado score, mean (SD) | 6.6 (1.6) | 7.0 (1.5) | 6.5 (1.6) |
| Duration of symptoms, d | |||
| <1 | 195 (25) | 39 (26) | 145 (25) |
| ≥1 | 580 (75) | 114 (75) | 436 (75) |
| Pain in previous 7 d, mean (SD) | 5.4 (3.0) | 5.9 (3.2) | 5.3 (2.9) |
| White blood cell count, mean (SD), /μL | 12 900 (4000) | 13 500 (3900) | 12 800 (4000) |
| Fever | |||
| None or NR | 582 (75) | 108 (70) | 443 (76) |
| Reported | 194 (25) | 46 (30) | 138 (24) |
| Nausea, vomiting, or anorexia | |||
| None or NR | 134 (17) | 32 (21) | 97 (17) |
| Reported | 641 (83) | 122 (79) | 483 (83) |
| Imaging test | |||
| Computed tomography alone | 626 (81) | 124 (81) | 468 (81) |
| Ultrasonography alone | 24 (3) | 6 (4) | 18 (3) |
| >1 imaging test | 125 (16) | 23 (15) | 95 (16) |
| Magnetic resonance imaging | 1 (<1) | 1 (1) | 0 (0) |
| Appendicolith | |||
| None or NR | 564 (73) | 89 (58) | 443 (76) |
| Reported | 212 (27) | 65 (42) | 138 (24) |
| Appendiceal diameter, mean (SD), mm | 11.5 (2.9) | 12.3 (3.1) | 11.3 (2.8) |
| Perforation, abscess, or appendiceal fat stranding present | |||
| None or NR | 646 (86) | 123 (84) | 487 (87) |
| Reported | 102 (14) | 24 (16) | 73 (13) |
Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); NR, not reported.
SI conversion factor: To convert white blood cells to ×109/L, multiply by 0.001.
For 41 participants, appendectomy status at 30 days was unknown. These participants are included in the overall data only. Missing data for other characteristics were race, 8 participants; health literacy help, 27 participants; federal poverty level or Medicaid status, 188 participants; modified Charlson comorbidity score, 3 participants; BMI, 174 participants; Alvarado score, 38 participants; duration of symptoms, 1 participant; pain in the last 7 days, 21 participants; white blood cell count, 3 participants; nausea, vomiting, or anorexia, 1 participant; appendiceal diameter, 103 participants; and perforation, 28 participants.
The most common response for other race was Hispanic.