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. 2021 Dec 14;23(2):142. doi: 10.3892/etm.2021.11065

Figure 3.

Figure 3

Effects of miR-126 mimic and PIK3R2-plasmid transfection on the viability, tube-forming ability and migration of EPCs under hypoxic conditions. EPCs were transfected with control-plasmid, PIK3R2-plasmid, mimic control, miR-126 mimic, miR-126 mimic + control-plasmid or miR-126 mimic + PIK3R2-plasmid under hypoxic conditions for 72 h. (A) MTT assay was performed to evaluate the cell viability of transfected EPCs. (B) Tube formation assay was used to measure the tube-forming ability of transfected EPCs. Magnification, x100. (C) Tube formation assay was quantified. (D) Transwell assay was used to measure the migration ability of transfected EPCs. Magnification, x200. (E) Transwell assay was quantified. **P<0.01 vs. Control. ##P<0.01 vs. hypoxia + mimic control. &&P<0.01 vs. hypoxia + miR-126 mimic + control-plasmid. miR, microRNA; PIK3R2, PI3K regulation subunit 2; OD, optical density; EPCs, endothelial progenitor cells.