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Acute effects of selective head cooling and subsequent rewarming on cerebral vasodilator functions. Vasodilator responses of pial arterioles to topical bradykinin (BK, 10−6 M), glutamate (Glu, 10−4 M), sodium nitroprusside (SNP, 10−5 M), and systemic hypercapnia were repeatedly tested during normothermia, head cooling, and rewarming. N = 9 pigs, 29 arterioles. Values are means ± SD. *P < 0.05 compared with normothermia responses. †P < 0.05 compared with responses during head cooling.
