Figure 2.

Adaptive eQTLs with strong signatures of positive selection

(A–C) Genomic regions flanking eQTLs with the highest PBS score for each continental population. LD-pruned adaptive eQTLs are represented by filled red circles, other eQTLs are represented by open black circles, and 1KGP SNPs are represented by open gray circles. hg19 coordinates are shown. Population-specific 99^th percentiles of PBS scores are represented by dashed red lines.

(D–F) Allele frequencies for 26 populations from the 1KGP (modified from the Geography of Genetics Variants Browser¹⁰⁵).