Skip to main content
. 2022 Jan 12;8(1):e654. doi: 10.1212/NXG.0000000000000654

Figure 2. Mutational Spectrum of South Africans With ALS.

Figure 2

(A) Schematic showing the numbers of likely pathogenic (LP) and pathogenic (P) variants, variants of uncertain significance (VUS), and likely benign (LB) variants identified in African ancestry patients with amyotrophic lateral sclerosis (ALS). C9orf72 refers to the pathogenic C9orf72 repeat expansion. (B) Graph showing gene counts of pathogenic (P) and variants of uncertain significance (VUS) in African ancestry patients with ALS. *Refers to prioritized VUS variants with a high likelihood of pathogenicity.