Table 3.
Perioperative kidney function
| Variable | Baseline | D0 | D1 | D2 | D3 | D4 | D5 |
|---|---|---|---|---|---|---|---|
| Creatinine (μmol/L) [IQR] | |||||||
| NEO | 753.0 [614.5-993.5] | 639.0 [527.7-870.0] | 558.0 [365.5-720.5] | 397.0 [202.5-643.5] | 253.0 [137.5-555.5] | 190.0 [121.5-439.5] | 170.0 [115.0-430.5] |
| SUG | 759.0 [585.5-948.5] | 596.0 [478.0-749.0] * | 504.0 [370.0-658.0] | 384.0 [170.0-596.5] | 214.0 [126.5-496.5] | 183.0 [117.0-433.5] | 162.0 [107.5-379.0] |
| Creatinine (μmol/L) [IQR] | |||||||
| SUG < 4 mg/kg (101 pts) | 757.0 [592.0-944.0] | 605.0 [502.0-744.0] | 484.0 [367.0-642.0] | 360.0 [170.0-611.0] | 228.0 [134.0-500.0] | 185.0 [126.0-437.0] | 168.0 [121.0-399.0] |
| SUG ≥ 4 mg/kg (74 pts) | 763.5 [573.0-953.0] | 564.5 [461.5-798.5] | 511.5 [378.5-680.5] | 400.5 [173.5-569.0] | 208.0 [119.7-494.0] | 169.0 [104.7-422.0] | 155.0 [100.0-362.0] |
| Urea (mmol/L) [IQR] | |||||||
| NEO | 18.7 [13.85-24.95] | 17.1 [13.1-22.0] | 17.5 [13.5-21.8] | 17.9 [12.4-24.9] | 16.4 [10.4-25.4] | 15.8 [9.9-27.6] | 14.7 [9.6-25.3] |
| SUG | 17.6 [13.62-23.6] | 14.9 [10.8-21.6] * | 15.3 [11.3-19.8] * | 15.9 [8.8-20.5] * | 14.9 [7.5-20.7] * | 14.2 [7.7-23.0] | 12.9 [7.7-24.7] |
| Urea (mmol/L) [IQR] | |||||||
| SUG < 4 mg/kg (101 pts) | 17.44 [13.93-24.09] | 15.48 [11.96-22.82] | 15.9 [11.5-19.7] | 16.4 [10.0-20.6] | 14.7 [8-20.8] | 14.4 [8.45-22.8] | 14.37 [8.2-23.9] |
| SUG ≥ 4 mg/kg (74 pts) | 17.6 [12.5-23.42] | 14.3 [10.3-20.64] | 14.45 [11.0-19.8] | 14.7 [7.45-20.47] | 15.1 [6.69-20.7] | 13.35 [7.12-23.32] | 12.5 [7.2-25.5] |
| eGFR [IQR] | |||||||
| NEO | 6.0 [5.0-8.0] | 8.0 [6.0-10.0] | 9.0 [7.0-14.0] | 13.0 [7.5-29.0] | 21.0 [9.0-43.5] | 31.0 [11.0-51.0] | 35.0 [12.2-53.7] |
| SUG | 6.0 [5.0-8.0] | 8.0 [6.0-11.0] * | 10.0 [7.0-14.5] | 14.0 [8.0-36.0] | 23.0 [10.0-52.5] | 32.0 [12.0-59.5] | 36.0 [14.0-61.0] |
| eGFR [IQR] | |||||||
| SUG < 4 mg/kg (101 pts) | 6.0 [5.0-8.0] | 8.0 [6.0-11.0] | 10.0 [7.0-15.0] | 15.0 [8.0-38.0] | 23.0 [10.0-52.0] | 32.0 [13.0-55.0] | 36.0 [14.0-56.0] |
| SUG ≥ 4 mg/kg (74 pts) | 6.0 [5.0-8.0] | 8.0 [6.0-10.0] | 9.0 [6.0-12.75] | 14.0 [8.0-33.75] | 26.0 [10.0-54.0] | 33.0 [12.0-63.75] | 37.0 [15.0-64.0] |
NMB neuromuscular block, NEO group of patients receiving neostigmine for reversal of cisatracurium-induced NMB, SUG group of patients receiving sugammadex for reversal of rocuronium-induced NMB, SUG <4 mg/kg and SUG ≥4 mg/kg sugammadex dose per kg of body weight for reversal of moderate or deep NMB, respectively, baseline value before kidney transplantation, DO-D5 values obtained the day of kidney transplantation (D0) and in each of the following five postoperative days (D1-D5), eGRF estimated glomerular filtration rate, creatinine and urea serum creatinine and serum urea, eGRF estimated glomerular filtration rate. Data are expressed as median [interquartile range, IQR]. (*) = significant p value (< 0.05) at intergroups analysis