Figure 3.

(a) Behavior of 3D skin models infected with T. rubrum, E. floccosum, S. brevicaulis, and C. albicans either untreated or after treatment with sertaconazole nitrate, ciclopirox olamine, or terbinafine, with regard to the viability of the cells in the full skin models. Release of (b) LDH and (c) IL‐1α as signs of damage to the full skin models, as well as monitoring of the secretion of the proinflammatory mediators (d) IL‐6 and (e) IL‐8. 3D, three‐dimensional; IL‐1α, interleukin 1α; LDH, lactate dehydrogenase