Figure A2.

Expanded C2 domain tree. Phylogenetic analysis of C2 domain homologs places the Chloroflexi within a diverse polyphyletic clade including Epsilonproteobacteria, Aquificae, Bacteroidetes, and Planctomycetes; this clade is sister to a broad radiation of Proteobacteria. Support values for selected bipartitions are labeled (aLRT/bb). Support for other nodes is indicated with the following color scheme: Strong support with both values ≥90 (black); weak support with both values ≤50 (white); intermediate support with one or both values between 50 and 90 (gray); conflicting support, with one value ≤50 and the other ≥90 (gray)