Table A1.
Open reading frame descriptions for SURF MAG 42, Pseudomonas aeruginosa PAO1, and Anaerolinea thermolimosa NirS gene neighborhoods
| Displayed ORF name | Expanded description | Protein ID | Source MAG/organism |
|---|---|---|---|
| Xylose isomerase‐like | Sugar phosphate isomerase/epimerase, xylose isomerase‐like TIM barrel | RJP53741.1 | SURF MAG 42 |
| LuxS | S‐ribosylhomocysteine lyase | RJP53742.1 | SURF MAG 42 |
| EEVS | 2‐Epi‐5‐epi‐valiolone synthase/iron‐containing alcohol dehydrogenase | RJP53743.1 | SURF MAG 42 |
| UbiG | Ubiquinone biosynthesis O‐methyltransferase/bifunctional 2‐polyprenol‐6‐hydroxyphenol | RJP53744.1 | SURF MAG 42 |
| UbiA | ubiA family prenyltransferase | RJP53745.1 | SURF MAG 42 |
| MhpC | Alpha/beta hydrolase/pimeloyl‐ACP methyl ester carboxylesterase | RJP53746.1 | SURF MAG 42 |
| UDG‐like | Uracil‐DNA glycosylase | RJP53748.1 | SURF MAG 42 |
| BaeS | HAMP domain‐containing protein/signal transduction kinase | RJP53750.1 | SURF MAG 42 |
| N‐acetyltransferase | GNAT family N‐acetyltransferase | RJP53751.1 | SURF MAG 42 |
| PrSA | Ribose‐phosphate pyrophosphokinase/phosphoribosylpyrophosphate synthetase | RJP53766.1 | SURF MAG 42 |
| PolX | DNA polymerase/3ʹ−5ʹ exonuclease | RJP53755.1 | SURF MAG 42 |
| YdcZ | DMT family transporter | RJP53756.1 | SURF MAG 42 |
| Putative PMT 2 superfamily | Dolichyl‐phosphate‐mannose‐protein mannosyltransferase | RJP53757.1 | SURF MAG 42 |
| Acetyl‐CoA dehydrogenase | Probable acyl‐CoA dehydrogenase | AAG03897.1 | PAO1 |
| nirN | Probable c‐type cytochrome | AAG03898.1 | PAO1 |
| SUMT | Probably uroporphyrin‐III c‐methyltransferase | AAG03899.1 | PAO1 |
| nirJ | Heme d1 biosynthesis protein NirJ | AAG03900.1 | PAO1 |
| nirH | Heme d1 biosynthesis protein NirH | AAG03901.1 | PAO1 |
| nirG | Heme d1 biosynthesis protein NirG/probable transcriptional regulator | AAG03902.1 | PAO1 |
| nirL | Heme d1 biosynthesis protein NirL | AAG03903.1 | PAO1 |
| nirD | Heme d1 biosynthesis protein nirD/probable transcriptional regulator | AAG03904.1 | PAO1 |
| nirF | Heme d1 biosynthesis protein NirF | AAG03905.1 | PAO1 |
| nirC | Probable c‐type cytochrome precursor | AAG03906.1 | PAO1 |
| nirM | Cytochrome c‐551 precursor | AAG03907.1 | PAO1 |
| nirQ | Regulatory protein NirQ | AAG03909.1 | PAO1 |
| Heme‐Cu oxidase III | Heme–copper oxidase, subunit III | AAG03911.1 | PAO1 |
| norC | Nitric‐oxide reductase subunit C | AAG03912.1 | PAO1 |
| norB | Nitric‐oxide reductase subunit B | AAG03913.1 | PAO1 |
| norD | Probable denitrification protein NorD | AAG03914.1 | PAO1 |
| Dnr | Transcriptional regulator DNR | AAG03916.1 | PAO1 |
| rsmY | Regulatory RNA RsmY/probable transcriptional regulator | AAG03917.1 | PAO1 |
| CynR | Provisional; DNA‐binding transcriptional regulator | AAG03917.1 | PAO1 |
| YiiM | Uncharacterized conserved protein/MOSC (molybdenum cofactor sulfurase C‐terminal)domain‐containing protein | AAG03918.1 | PAO1 |
| ArgD | Acetylornithine/succinyldiaminopimelate/putrescin e aminotransferase | AAG03919.1 | PAO1 |
| TrpB‐like | TrpB‐like pyridoxal‐phosphate dependent enzyme | GAP05449.1 | Anaerolinea thermolimosa |
| Gph | Phosphoglycolate phosphatase; haloacid dehalogenase family hydrolase | GAP05450.1 | Anaerolinea thermolimosa |
| DR1245‐like | Uncharacterized, YbjN domain‐containing protein; possible type III secretion system chaperone protein | GAP05451.1 | Anaerolinea thermolimosa |
| peptidase C39‐like | Peptidase C39‐like and TPR domain‐containing protein | GAP05452.1 | Anaerolinea thermolimosa |
| DUF2568 | Hypothetical protein; YrdB family; DUF2568 | GAP05453.1 | Anaerolinea thermolimosa |
| DUF4388 | Hypothetical protein; DUF4388 | GAP05454.1 | Anaerolinea thermolimosa |
| Srp102 | ATP/GTP‐binding protein; GTPase, signal recognition particle receptor subunit beta | GAP05455.1 | Anaerolinea thermolimosa |
| MhpC | Predicted alpha/beta hydrolase; pimeloyl‐ACP methyl ester carboxylesterase | GAP05456.1 | Anaerolinea thermolimosa |
| glmU | N‐acetylglucosamine‐1‐phosphate uridyltransferase; left‐handed parallel beta‐helix domain | GAP05458.1 | Anaerolinea thermolimosa |
| Cytochrome cd1 | Protein containing cytochrome D1 heme domain; nitrite reductase | GAP05460.1 | Anaerolinea thermolimosa |
| Cytidylate kinase‐like | Cytidylate kinase‐like family protein; NK superfamily | GAP05462.1 | Anaerolinea thermolimosa |
| Glycosyl hydrolase catalytic core | Glycosyl hydrolases superfamily | GAP05463.1 | Anaerolinea thermolimosa |
| Protoheme IX farnesyltransferase | Provisional protoheme IX farnesyltransferase; cytochrome oxidase assembly protein superfamily | GAP05464.1 | Anaerolinea thermolimosa |
| SURF1 | SURF1 superfamily; similar to yeast cytochrome oxidase assembly protein SHY1 | GAP05465.1 | Anaerolinea thermolimosa |
| SCO | SCO1/SenC/PrrC; synthesis of cytochrome c oxidase family | GAP05467.1 | Anaerolinea thermolimosa |
| Heme Cu oxidase III | Heme–copper oxidase subunit III | GAP05468.1 | Anaerolinea thermolimosa |
| COX4 pro | Cytochrome c oxidase subunit IV family protein; prokaryotic cytochrome C oxidase subunit IV | GAP05469.1 | Anaerolinea thermolimosa |
| Heme Cu oxidase I | Heme–copper oxidase subunit I | GAP05470.1 | Anaerolinea thermolimosa |
| CyoA | Cytochrome c oxidase, subunit II; cytochrome c | GAP05471.1 | Anaerolinea thermolimosa |
Abbreviations: MAG, metagenome‐assembled genome; SURF, Sanford Underground Research Facility.