Table 1:

The associations of adipose tissue with the development of segment-level coronary artery stenosis progression

	Univariate IRR (95% CI); P value	Minimally adjusted IRR (95% CI); (P value)	Fully adjusted IRR (95% CI); (P value)
VAT in the total population	1.41 (1.16–1.71); p<0.001	1.24 (1.00–1.52); p=0.046	1.10 (0.83–1.45); p=0.52
VAT in men with HIV	1.35 (1.05–1.73); p<0.05	1.11 (0.84–1.46); p=0.48	0.93 (0.65–1.33); p=0.70
VAT in men without HIV	1.52 (1.13–2.05); p<0.01	1.41 (1.02–1.94) (P<0.05)	1.48 (0.93–2.36); p=0.10
Abdominal SAT in the total population	0.98 (0.81–1.20); p=0.88	1.01 (0.82–1.25); p=0.90	0.96 (0.70–1.33); p=0.81
Abdominal SAT in men with HIV	0.91 (0.71–1.17); p=0.47	0.94 (0.72–1.23); p=0.66	0.94 (0.64–1.39); p=0.75
Abdominal SAT in men without HIV	1.24 (0.89–1.72); p=0.20	1.20 (0.85–1.69); p=0.31	1.29 (0.67–2.50); p=0.45
Thigh SAT in the total population	0.83 (0.67–1.02); p=0.08	0.93 (0.74–1.18); p=0.62	0.94 (0.70–1.26); p=0.69
Thigh SAT in men with HIV	0.78 (0.59–1.04); p=0.10	0.93 (0.69–1.25); p=0.62	0.94 (0.64–1.39); p=0.82
Thigh SAT in men without HIV	1.01 (0.69–1.48); p=0.96	0.98 (0.66–1.46); p=0.93	0.82 (0.45–1.51); p=0.53

IRR = incidence rate ratio; CI = confidence interval; NS = not significant; VAT = visceral adipose tissue; SAT = subcutaneous adipose tissue

^*Minimally adjusted models included: age, race, and study center.

^**Fully adjusted models included the following covariates in addition to the minimally adjusted models: high density lipoprotein cholesterol, total cholesterol, use of lipid lowering medication, systolic blood pressure, use of antihypertensive medication, fasting glucose, diabetes, smoking pack years, body mass index (BMI), and an interaction term between HIV serostatus and adipose tissue. Results of the fully adjusted models that included the aforementioned variables, excluding BMI, are not shown here.

^***Separate models were created for the total study population, men with HIV, and men without HIV.