Table 2. Residual Solvent Profile of cGMP MDMA·HCl.
solvent | acceptance criteria (ppm) | highest level found (ppm) |
---|---|---|
THF | 720 | <7 |
tert-Butyl methyl ether (TBME) | 5000 | not detected |
n-Heptane | 5000 | <67 |
methanol | 3000 | <6 |
2-propanol | 5000 | 509 |
dichloromethane (DCM) | 600 | not detected |