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. 2021 Dec 20;7(1):900–907. doi: 10.1021/acsomega.1c05520

Table 2. Residual Solvent Profile of cGMP MDMA·HCl.

solvent acceptance criteria (ppm) highest level found (ppm)
THF 720 <7
tert-Butyl methyl ether (TBME) 5000 not detected
n-Heptane 5000 <67
methanol 3000 <6
2-propanol 5000 509
dichloromethane (DCM) 600 not detected