Table 2.
Measured (MEC) and Predicted (UW-TTURC) Nicotine Biomarkers by Sex and Ethnicity, African American and White
| Female | Male | African American | White | |||||
|---|---|---|---|---|---|---|---|---|
| Biomarker | Mean | (SE) | Mean | (SE) | Mean | (SE) | Mean | (SE) |
| Measured | N = 500 | N = 301 | N = 364 | N = 437 | ||||
| uNMRa | 1.48b | (0.03) | 1.36b | (0.04) | 1.45 | (0.04) | 1.40 | (0.04) |
| uNMRCPD | 1.20 | (0.06) | 1.09 | (0.06) | 1.44 | (0.07) | 1.32 | (0.07) |
| TNEc | 8.03b | (0.12) | 7.71b | (0.13) | 7.27b | (0.12) | 8.32b | (0.11) |
| TNECPD | 7.43b | (0.18) | 6.42b | (0.18) | 6.99 | (0.20) | 7.42 | (0.20) |
| Predicted | N = 1090 | N = 774 | N = 260 | N = 1604 | ||||
| uNMR | 1.46 | (0.01) | 1.45 | (0.01) | 1.52b | (0.01) | 1.45b | (0.01) |
| TNE | 8.46b | (0.04) | 7.91b | (0.04) | 7.43b | (0.06) | 8.36b | (0.03) |
For measured nicotine biomarker values by sex, values are adjusted by age and ethnicity (and CPD, where indicated), and ethnicity strata values are adjusted by age and sex (and CPD, where indicated). For predicted nicotine biomarker values, age, sex, and ethnicity (and CPD, where indicated) were included in the models. CPD = cigarettes per day; MEC = Multiethnic Cohort; TNE = total nicotine equivalents; uNMR = urinary nicotine metabolite ratio; UW-TTURC = University of Wisconsin Transdisciplinary Tobacco Use Research Center.
aNatural log transformed, no units.
b p < .001.
cSquare root transformed, nmol/mg creatinine.