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. 2021 Jul 27;23(12):2162–2169. doi: 10.1093/ntr/ntab124

Table 4.

Predicted Biomarkers and Nicotine Dependence Measures, UW-TTURC

Dependence uNMR TNE
Measure N Coefficient SE Coefficient SE
FTND
 Total 1843 0.129 0.195 0.099a 0.045
 CPD 1862 0.211b 0.068 0.039a 0.016
 TTFC 1861 −0.008 0.078 0.041a 0.018
WISDM
 Automaticity 1800 0.297a 0.151 −0.011 0.035
 Loss of control 1800 −0.021 0.127 0.033 0.029
 Craving 1800 −0.156 0.120 0.025 0.028
 Tolerance 1800 0.147 0.127 0.060a 0.029
 Total PDM 1800 −0.003 1.183 −0.065 0.273
NDSS
 Drive 1809 −0.062 0.096 0.005 0.022
 Priority 1820 0.019 0.097 −0.033 0.022
 Tolerance 1814 0.239a 0.104 0.032 0.024
 Continuity 1815 0.033 0.094 0.015 0.022
 Stereotypy 1813 −0.012 0.096 0.066b 0.022
 NDSS-T 1800 0.008 0.086 0.022 0.020

CPD = cigarettes per day; FTND = Fagerström Test of Nicotine Dependence; NDSS = Nicotine Dependence Syndrome Scale; NDSS-T = NDSS Total; TNE = total nicotine equivalents; Total PDM = sum of four Primary Dependence Motives; TTFC = time-to-first-cigarette; uNMR = urinary nicotine metabolite ratio; UW-TTURC = University of Wisconsin Transdisciplinary Tobacco Use Research Center; WISDM = Wisconsin Inventory of Smoking Dependence Motives.

a p < .05.

b p < .005.