Scheme 1. Reagents and Conditions: (a) 4-Nitrophenyl Chloroformate, Pyridine, DCM, rt; (b) Exatecan, DMAP, DMF, rt; (c) N3PEG4NHBoc, Cu(MeCN)4PF6, DCM, rt; (d) TFA, DCM, rt; and (e) EMCS, DIPEA, DCM, rt.
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