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. 2021 Dec 30;7(1):1082–1089. doi: 10.1021/acsomega.1c05671

Table 1. Rate of Binding to Albumin of the Prodrug Mal-azo-Exatecan in Murine, Rat, and Human Plasma.

  albumin binding
  time (min) bound (%)
murine plasma 2 95.81 ± 0.06
8 99.55 ± 0.11
rat plasma 2 96.77 ± 0.15
8 99.38 ± 0.12
human plasma 0.25 99.51 ± 0.01
2 100 ± 0.00
HSA 2 89.41 ± 0.05
8 99.50 ± 0.13