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. 2022 Jan 13;10(3):742–750.e14. doi: 10.1016/j.jaip.2021.12.034

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© 2022 American Academy of Allergy, Asthma & Immunology.

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Predicted probabilities of coronavirus disease 2019–related (A) hospitalization, (B) admission to the intensive care unit (ICU), and (C) hospital mortality as a function of baseline peripheral blood absolute eosinophil count (AEC), stratified by inhaled corticosteroids (ICS) use. These interaction plots show that the association between coronavirus disease 2019–related outcomes and AEC depends on the use of ICS (all P values for interaction < .001). The probabilities were calculated by fitting a logistic regression using a restricted cubic spline function for the AEC (log10-transformed). The 95% confidence intervals are indicated by the shaded area around the fitted line.